产品: TOM1L1 抗体
货号: DF15773
描述: Rabbit polyclonal antibody to TOM1L1
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 53kD(Calculated).
蛋白号: O75674

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
TOM1L1 Antibody detects endogenous levels of TOM1L1.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

2310045L10Rik; C80573; OK/KNS CL.3; Src activating and signaling molecule; Src activating and signaling molecule protein; Src-activating and signaling molecule protein; SRCASM; Target of Myb like protein 1; Target of Myb-like protein 1; Target of myb1 (chicken) homolog like 1; Target of myb1 (chicken) like 1; Target of myb1 like 1; TM1L1_HUMAN; TOM1 L1; TOM1 like protein 1; TOM1-like protein 1; TOM1L1; TOM1L1 protein;

抗原和靶标

免疫原:

A synthesized peptide derived from human TOM1L1.

Uniprot:
基因/基因ID:
序列:
MAFGKSHRDPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYEEIDAHQHKGAQNDGD

研究背景

功能:

Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).

翻译修饰:

Phosphorylated on tyrosines by FYN and LYN.

细胞定位:

Golgi apparatus>Golgi stack. Endosome membrane. Cytoplasm. Membrane>Peripheral membrane protein>Cytoplasmic side.
Note: A small proportion is membrane-associated.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Interacts with FYN, GRB2 and PIK3R1 when phosphorylated. Interacts with LYN.

蛋白家族:

Belongs to the TOM1 family.

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