PKD1/PKC mu Antibody - #AF6443

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产品: PKD1/PKC mu 抗体
货号: AF6443
描述: Rabbit polyclonal antibody to PKD1/PKC mu
应用: WB IHC IF/ICC
文献验证: IHC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: Q15139
RRID: AB_2835267

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
PKD1/PKC mu Antibody detects endogenous levels of total PKD1/PKC mu.
RRID:
AB_2835267
引用格式: Affinity Biosciences Cat# AF6443, RRID:AB_2835267.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

KPCD1_HUMAN; nPKC D1; nPKC mu; nPKC-D1; nPKC-mu; nPKCD1; nPKCmu; PKC; PKC MU; PKCM; PKCmu; PKD 1; PKD; PKD1; PRKCM; PRKD 1; Prkd1; Protein kinase C mu; Protein kinase C mu type; Protein kinase D; Protein kinase D1; Serine/threonine protein kinase D1; Serine/threonine-protein kinase D1;

抗原和靶标

免疫原:

A synthesized peptide derived from human PKD1/PKC mu, corresponding to a region within the internal amino acids.

基因/基因ID:
PRKD1(5587)
描述:
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information.

研究领域

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.

文献引用

1). Angiogenic function of astragaloside IV in rats with myocardial infarction occurs via the PKD1-HDAC5-VEGF pathway. Experimental and Therapeutic Medicine, 2019 (PubMed: 30906439) [IF=2.4]

Application: IHC    Species: rat    Sample: myocardium

Figure 5.| Effect of AS‑IV on the protein expression of PKD1, HDAC5 and VEGF in rats with myocardial infarction. Immunohistochemistry was performed to detect protein expression. Representative and quantitative immunohistochemistry results are presented in the upper and lower panel. Blue arrows represent positive cells for PKD1 expression, red arrows represent the positive cells for HDAC5 expression and green arrows represent the positive cells for VEGF expression. Data are presented as the mean ± standard deviation (n=6‑8). Magnification, x400; scale bar, 50 µm. **P<0.01 vs. the AS‑IV group; ##P<0.01 vs. the AS‑IV‑CID755673 group; $P<0.05 vs. the Model group; &P<0.05 vs. the CID755673 group. AS‑IV, astragaloside IV; PKD1, protein kinase D1; HDAC5, class IIa histone deacetylase 5; VEGF, vascular endothelial growth factor.

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