产品: IFITM5 抗体
货号: DF15504
描述: Rabbit polyclonal antibody to IFITM5
应用: IHC
反应: Human
分子量: 14kD(Calculated).
蛋白号: A6NNB3

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 100ul RMB¥ 2300 现货
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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
IFITM5 Antibody detects endogenous levels of IFITM5.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Fragilis4; Hrmp1; IFITM5; IFM5_HUMAN; Interferon-induced transmembrane protein 5;

抗原和靶标

免疫原:

A synthesized peptide derived from human IFITM5.

Uniprot:
基因/基因ID:
表达:
A6NNB3 IFM5_HUMAN:

Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (at protein level) (PubMed:24519609). Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (PubMed:24519609).

序列:
MDTAYPREDTRAPTPSKAGAHTALTLGAPHPPPRDHLIWSVFSTLYLNLCCLGFLALAYSIKARDQKVVGDLEAARRFGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLARLAKDSAAFFSTKFDDADYD

研究背景

功能:

Required for normal bone mineralization.

翻译修饰:

Palmitoylated.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Detected in bone. Detected in osteoblasts and fibroblasts (at protein level). Detected in bone. Detected in osteoblasts and fibroblasts.

亚基结构:

Interacts with FKBP11.

蛋白家族:

Belongs to the CD225/Dispanin family.

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