(2)
(4)
产品描述
来源:
Rabbit
应用:
IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human, Mouse
克隆:
Polyclonal
特异性:
FUNDC1 antibody detects endogenous levels of FUNDC1.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
FUN14 domain containing 1; FUN14 domain containing protein 1; FUN14 domain-containing protein 1; FUND1_HUMAN; fundc1;
抗原和靶标
文献引用
1). FUNDC1 deficiency aggravates endothelial senescence and retinal dysfunction. Biochimica et biophysica acta. Molecular basis of disease, 2026
(PubMed: 41135636)
[IF=4.2]
2). Ginsenoside Rh1 Alleviates Allergic Rhinitis by Mediating Mitochondrial Autophagy via Activation of the AMPK/ULK1/FUNDC1 Pathway. Food science & nutrition, 2025
(PubMed: 40535916)
[IF=3.5]
Application: WB Species: Mouse Sample:
FIGURE 3 Ginsenoside Rh1 activates the AMPK/ULK1/FUNDC1 pathway to enhance mitochondrial autophagy in AR mice. (A) Venn diagram illustrating the overlap between AR and the targets of Ginsenoside Rh1. (B) PPI network highlighting interactions among key targets, including AMPK (PRKAG1), ULK1, and FUNDC1. (C) GO analysis of the three biological ontologies. (D) The chemical structure of Ginsenoside Rh1. (E) MD of Ginsenoside Rh1 and AMPK. (F) WB analysis demonstrating protein levels of AMPK, ULK1, and FUNDC1, as well as their phosphorylated forms. (G) WB results showing the protein levels of PINK1 and Parkin. (H, I) IF detection of PINK1 and Parkin in the nasal mucosa. Data are presented as mean ± SD (n = 8). *p
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