产品: OSBPL11 抗体
货号: DF15433
描述: Rabbit polyclonal antibody to OSBPL11
应用: WB IHC IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse
蛋白号: Q9BXB4

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
OSBPL11 Antibody detects endogenous levels of OSBPL11.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ13012; FLJ13164; ORP 11; ORP-11; ORP11; OSB11_HUMAN; OSBP related protein 11; OSBP-related protein 11; OSBP12; OSBPL11; OTTHUMP00000215865; Oxysterol binding protein like 11; Oxysterol binding protein related protein 11; Oxysterol-binding protein-related protein 11; TCCCIA00292;

抗原和靶标

免疫原:

A synthesized peptide derived from human OSBPL11.

基因/基因ID:

文献引用

1). High level expression of OSBPL11 is associated with atherosclerosis and Alzheimer's disease. Inflammation, 2025 (PubMed: 40407857) [IF=4.5]

Application: IF/ICC    Species: human    Sample:

Fig. 3 Increased expression of OSBPL11 in AS and AD patients. (A) HE and Masson staining of arterial vessels in healthy control and AS patients (Scale bar: 200 μm). (B) Immunohistochemical staining for OSBPL11 expression in healthy control and AS patients (brown-yellow indicates positive staining area, from left to right magnification: 4x; 40x, **P 

Application: WB    Species: Mouse    Sample:

Fig. 5 Increased expression of OSBPL11 in high fat diet fed ApoE−/− mice. (A) Co-localization of OSBPL11 with macrophages in the aorta of ApoE−/− mice (Right fluorescence plot is a merge of the left single-channel fluorescence plot; Scale bar: 75 μm, DAPI in blue fluorescence indicates cell nuclei, CD68 in red fluorescence indicates macrophages, OSBPL11 in green, n = 6). (B) Co-localization of OSBPL11 with astrocytes in the brain of ApoE−/− mice (Scale bar: 150 μm; DAPI in blue fluorescence indicates cell nuclei, GFAP in red fluorescence indicates astrocytes, OSBPL11 in green, n = 6). (C-D) Immunohistochemical staining for OSBPL11 expression in the aorta and the brain of ApoE−/− mice (left to right magnification: 4x; 40x, n = 6). (E–F) Real-time quantitative PCR was performed to detect the expression of OSBPL11 in the aorta and the brain of ApoE−/− mice. (G-H) Western blotting shows the expression of OSBPL11 in the aorta and the brain of ApoE−/− mice. (**P 

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