产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
ABP; Androgen binding protein; SBP; Sex hormone-binding globulin; Sex steroid binding protein; Sex steroid-binding protein; SHBG; SHBG_HUMAN; TeBG; Testis specific androgen binding protein; Testis-specific androgen-binding protein; Testosterone binding beta globulin; Testosterone estradiol binding globulin; Testosterone estrogen binding globulin; Testosterone-estradiol-binding globulin; Testosterone-estrogen-binding globulin;
抗原和靶标
A synthesized peptide derived from human SHBG.
- P04278 SHBG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSFCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
研究背景
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Variant Asn-356 contains one N-linked (GlcNAc...) at position 356.
Secreted.
Note: In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Isoform 1 and isoform 2 are present in liver and testis.
Homodimer.
限制条款
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