产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
bA514O12.3; Ribonuclease 6; Ribonuclease T2; RNASE6PL; Rnaset2; RNT2_HUMAN; RP11 514O12.3;
抗原和靶标
A synthesized peptide derived from human RNASET2.
Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain.
- O00584 RNT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDYWTIHGLWPDKSEGCNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRVCEDGPVFYPPPKKTKH
研究背景
Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism.
Secreted. Lysosome lumen. Endoplasmic reticulum lumen.
Note: Subcellular fractionation of transfected ovarian cancer cells reveals full-length RNASET2 in the endoplasmic reticulum fraction and the 2 smaller RNASET2 proteolytic products in the lysosome fraction.
Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain.
Belongs to the RNase T2 family.
限制条款
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