产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
C13orf17; DCN1 like protein 2; DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae); DCN1-like protein 2; DCNL2_HUMAN; DCUN1 domain-containing protein 2; DCUN1D2; DCUN1L2; Defective in cullin neddylation protein 1-like protein 2; FLJ10704; FLJ20092; OTTHUMP00000018776;
抗原和靶标
A synthesized peptide derived from human DCUN1D2.
- Q6PH85 DCNL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAWPVLIDDFVEYARPVVTGGKRSLF
研究背景
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
The DCUN1 domain, also known as PONY domain mediates recognition of the N-terminally acetylated NEDD8-conjugating E2 enzyme.
限制条款
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