MCUR1 Antibody - #DF14777

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产品: MCUR1 抗体
货号: DF14777
描述: Rabbit polyclonal antibody to MCUR1
应用: ELISA(peptide)
反应: Human, Mouse
分子量: 40kD(Calculated).
蛋白号: Q96AQ8

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
MCUR1 Antibody detects endogenous levels of MCUR1.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C6orf79; CC90A_HUMAN; Ccdc90a; Coiled coil domain containing 90A; Coiled coil domain containing protein 90A, mitochondrial; Coiled-coil domain-containing protein 90A; FLJ20958; mitochondrial;

抗原和靶标

免疫原:

A synthesized peptide derived from human MCUR1.

Uniprot:

Q96AQ8(MCUR1_HUMAN) >>Visit HPA database.

基因/基因ID:
MCUR1(63933)
表达:
Q96AQ8 MCUR1_HUMAN:

Ubiquitously expressed.

序列:
MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGVSRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAAGALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI

研究背景

功能:

Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU. Probably involved in the assembly of the membrane components of the uniporter complex (uniplex).

细胞定位:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitously expressed.

亚基结构:

Interacts (via coiled coil regions) with MCU; the interaction is direct. Interacts with SMDT1/EMRE; the interaction is direct. Interacts with PPIF.

蛋白家族:

Belongs to the CCDC90 family.

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