Sumo1 Antibody - #AF0280

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产品: Sumo1 抗体
货号: AF0280
描述: Rabbit polyclonal antibody to Sumo1
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Dog, Chicken
蛋白号: P63165
RRID: AB_2833449

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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实验方案
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC: 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Sumo1 Antibody detects endogenous levels of total Sumo1.
RRID:
AB_2833449
引用格式: Affinity Biosciences Cat# AF0280, RRID:AB_2833449.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DAP1; GAP modifying protein 1; GAP-modifying protein 1; GMP 1; GMP1; OFC10; PIC 1; PIC1; SENP2; Sentrin 1; Sentrin; Small ubiquitin related modifier 1; Small ubiquitin-like modifier 1; Small ubiquitin-related modifier 1; SMT3; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3, yeast, homolog 3; Smt3C; SMT3H3; SUMO-1; SUMO1; SUMO1_HUMAN; Ubiquitin homology domain protein PIC1; Ubiquitin Like 1; Ubiquitin like protein SMT3C; Ubiquitin like protein UBL1; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Ubiquitin-like protein UBL1; UBL 1; UBL1;

抗原和靶标

免疫原:

A synthesized peptide derived from human Sumo1, corresponding to a region within N-terminal amino acids.

基因/基因ID:
SUMO1(7341)
描述:
SUMO1 Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.

研究领域

· Genetic Information Processing > Translation > RNA transport.

文献引用

1). SUMOylation of Vps34 by SUMO1 promotes phenotypic switching of vascular smooth muscle cells by activating autophagy in pulmonary arterial hypertension. PULMONARY PHARMACOLOGY & THERAPEUTICS, 2019 (PubMed: 30703554) [IF=3.3]

Application: WB    Species: mouse    Sample: lung

Fig. 2 |Association of increased SUMO1 expression with activation of autophagy in PAH.(A) Western blot analysis using lung tissue samples showed significantly increased expression levels of SUMO1, HIF-1α and autophagy marker LC3b, and a significantly decreased expression level of autophagy marker p62 in hypoxic PAH mice than in control mice. (B) The Western blotting data in (A) were quantified and plotted. (n=6/group,*P<0.05, **P<0.01).

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