CD161 Antibody - #DF14429

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产品: CD161 抗体
货号: DF14429
描述: Rabbit polyclonal antibody to CD161
应用: WB
文献验证: WB
反应: Human, Mouse, Rat
蛋白号: Q12918

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
CD161 Antibody detects endogenous levels of total CD161.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C-type lectin domain family 5 member B; CD161; CLEC5B; HNKR-P1a; Killer Cell Lectin like Receptor Subfamily B Member 1; Killer cell lectin-like receptor subfamily B member 1; KLRB1; KLRB1_HUMAN; Natural killer cell surface protein P1A; NKR; NKR P1; NKR-P1A; NKRP1; NKRP1A;

抗原和靶标

免疫原:

A synthesized peptide derived from Human CD161.

基因/基因ID:
KLRB1(3820)

研究领域

· Human Diseases > Infectious diseases: Parasitic > Malaria.

文献引用

1). Targeting CD161 inhibitory receptors enhances NK cell-mediated changes in synovial fibroblast function in rheumatoid arthritis. International immunopharmacology, 2025 (PubMed: 40945032) [IF=4.8]

Application: WB    Species: human    Sample: NK cells

Fig. 1. CD161 is highly expressed in RA and may mainly be expressed in NK cells. (A) Expression of CD161 in GSE89408. OA: Osteoarthritis. (B,C) WB and q-PCR expression of CD161 in synovium of clinical patients with RA and OA. *: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001. (D) Distribution of subgroups and CD161 expression in PBMCs of 36 human individuals. (E) Distribution of CD161 expression in the GPI synovial single-cell dataset GSE184609. (F) The proportion of various subgroups in human PBMCs in RA and control group. (G) The proportion of various subgroups in GSE184609. (H) The expression of CD56 in synovial tissue sections of trauma control group (8 samples), OA group (8 samples), and RA group. (I) Statistical analysis of immunohistochemistry results in (H). ns: no significant.

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