产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
2410002I16Rik; 5830420C16Rik; AI426635; CFP 1; CFP1; CpG binding protein; CpG-binding protein; CXXC 1; CXXC finger 1; CXXC finger 1 PHD domain; CXXC finger protein 1; CXXC type zinc finger protein 1; CXXC-type zinc finger protein 1; CXXC1; CXXC1_HUMAN; DNA binding protein with PHD finger and CXXC domain; hCGBP; HsT2645; PCCX 1; PCCX1; PHD finger and CXXC domain containing protein 1; PHD finger and CXXC domain-containing protein 1; PHF 18; PHF18; Protein containing CXXC domain 1; SPP 1; SPP1; ZCGPC 1; ZCGPC1; Zinc finger, CpG binding type containing 1;
抗原和靶标
A synthesized peptide derived from Human CGBP.
- Q9P0U4 CXXC1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
研究背景
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
May be regulated by proteolysis.
Nucleus speckle. Nucleus.
Note: Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
Ubiquitous.
Component of the SET1 complex, at least composed of the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1 HCFC1 and DPY30. Interacts with SETD1A. Interacts with ZNF335. Interacts with PRDM9; this interaction does not link PRDM9-activated recombination hotspot sites with DSB machinery and is not required for the hotspot recognition pathway. Interacts with histone H3K4me3 (By similarity).
The acidic domain carries the potential to activate transcription.
限制条款
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