CHST6 Antibody - #DF14345

(2)  
产品: CHST6 抗体
货号: DF14345
描述: Rabbit polyclonal antibody to CHST6
应用: IHC IF/ICC
反应: Human
分子量: 44kD(Calculated).
蛋白号: Q9GZX3

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 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
CHST6 Antibody detects endogenous levels of total CHST6.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C GlcNAc6ST; C-GlcNAc6ST; Carbohydate sulfotransferase 6; Carbohydrate (N acetylglucosamine 6 O) sulfotransferase 6; Carbohydrate sulfotransferase 6; CHST6; CHST6_HUMAN; Corneal GlcNAc6-sulfotransferase; Corneal N acetylglucosamine 6 sulfotransferase; Corneal N-acetylglucosamine-6-O-sulfotransferase; Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 4 beta; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta; GlcNAc6ST 5; GlcNAc6ST-5; Gn6st-5; GST4 beta; GST4-beta; hCGn6ST; N-acetylglucosamine 6-O-sulfotransferase 5;

抗原和靶标

免疫原:

A synthesized peptide derived from Human CHST6.

Uniprot:

Q9GZX3(CHST6_HUMAN) >>Visit HPA database.

基因/基因ID:
CHST6(4166)
表达:
Q9GZX3 CHST6_HUMAN:

Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea.

序列:
MWLPRVSSTAVTALLLAQTFLLLFLVSRPGPSSPAGGEARVHVLVLSSWRSGSSFVGQLFNQHPDVFYLMEPAWHVWTTLSQGSAATLHMAVRDLVRSVFLCDMDVFDAYLPWRRNLSDLFQWAVSRALCSPPACSAFPRGAISSEAVCKPLCARQSFTLAREACRSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPGLRVVREVCRSHVRIAEAATLKPPPFLRGRYRLVRFEDLAREPLAEIRALYAFTGLSLTPQLEAWIHNITHGSGPGARREAFKTSSRNALNVSQAWRHALPFAKIRRVQELCAGALQLLGYRPVYSEDEQRNLALDLVLPRGLNGFTWASSTASHPRN

研究背景

功能:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.

细胞定位:

Golgi apparatus membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea.

蛋白家族:

Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.

研究领域

· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - keratan sulfate.

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