HS3ST1 Antibody - #DF14125

(4)  
产品: HS3ST1 抗体
货号: DF14125
描述: Rabbit polyclonal antibody to HS3ST1
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 35-50kD; 36kD(Calculated).
蛋白号: O14792

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
HS3ST1 Antibody detects endogenous levels of total HS3ST1.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

3-OST-1; 3OST; 3OST1; EC 2.8.2.23; h3 OST 1; h3-OST-1; Heparan sulfate (glucosamine) 3 O sulfotransferase 1; Heparan sulfate 3 O sulfotransferase 1; Heparan sulfate 3-O-sulfotransferase 1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Heparan sulfate glucosamine 3-O-sulfotransferase 1; Heparin glucosamine 3 O sulfotransferase; HS3S1_HUMAN; HS3ST 1; Hs3st1;

抗原和靶标

免疫原:

A synthesized peptide derived from Human HS3ST1.

Uniprot:

O14792(HS3S1_HUMAN) >>Visit HPA database.

基因/基因ID:
HS3ST1(9957)
表达:
O14792 HS3S1_HUMAN:

Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.

序列:
MAALLLGAVLLVAQPQLVPSRPAELGQQELLRKAGTLQDDVRDGVAPNGSAQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTVEKTPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLVRDGRLNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGRDRCLHESKGRAHPQVDPKLLNKLHEYFHEPNKKFFELVGRTFDWH

研究背景

功能:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.

细胞定位:

Golgi apparatus lumen.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.

蛋白家族:

Belongs to the sulfotransferase 1 family.

研究领域

· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - heparan sulfate / heparin.

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