Vinculin Antibody - #AF6206

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产品: Vinculin 抗体
货号: AF6206
描述: Rabbit polyclonal antibody to Vinculin
应用: WB IHC IF/ICC
文献验证: IF/ICC
反应: Human, Mouse, Rat, Monkey
预测: Pig, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: P18206
RRID: AB_2835087

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
Vinculin Antibody detects endogenous levels of total Vinculin.
RRID:
AB_2835087
引用格式: Affinity Biosciences Cat# AF6206, RRID:AB_2835087.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; OTTHUMP00000019861; OTTHUMP00000019862; VCL; VINC; VINC_HUMAN; Vinculin;

抗原和靶标

免疫原:

A synthesized peptide derived from human Vinculin, corresponding to a region within the internal amino acids.

基因/基因ID:
VCL(7414)
描述:
Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and α-actinin. In addition, vinculin, Talin and α-actinin each contain Actin binding sites. Expression of vinculin and Talin has been shown to be affected by the level of Actin expression.

研究领域

· Cellular Processes > Cellular community - eukaryotes > Focal adhesion.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Adherens junction.   (View pathway)

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Bacterial invasion of epithelial cells.

· Human Diseases > Infectious diseases: Bacterial > Shigellosis.

· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.

· Organismal Systems > Immune system > Leukocyte transendothelial migration.   (View pathway)

文献引用

1). CALD1 inhibits invasion of human ovarian cancer cells by affecting cytoskeletal structure and the number of focal adhesion. Translational cancer research, 2025 (PubMed: 40104711) [IF=1.5]

Application: IF/ICC    Species: human    Sample: SK-OV-3 cells

Figure 7. Immunofluorescence staining images of the focal adhesion marker Vinculin (red) in different SK-OV-3 cell groups. Nuclei were stained using DAPI (blue). The right-side images are approximately two times magnified compared to the corresponding areas in the left images.

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