产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
FLJ11693; FLJ14154; HAT4; Histone acetyltransferase type B protein 4; N acetyltransferase 15 (GCN5 related, putative); N alpha acetyltransferase 60; N(alpha) acetyltransferase 60, NatF catalytic subunit; N-acetyltransferase 15; N-alpha-acetyltransferase 60; naa60; NAA60_HUMAN; NAT15; NatF catalytic subunit;
抗原和靶标
A synthesized peptide derived from Human FLJ14154.
- Q9H7X0 NAA60_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKEDGDILASNFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFKQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALASLSPCSIPHRVYRQAHSLLCSFLPWSGISSKSGIEYSRTM
研究背景
N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences.
Acetylated: autoacetylation is required for optimal acetyltransferase activity.
Golgi apparatus membrane>Peripheral membrane protein>Cytoplasmic side.
Note: Probably forms an intramembrane hairpin-like structure in the membrane.
Monomer and homodimer; monomer in presence of substrate and homodimer in its absence.
Belongs to the acetyltransferase family. NAA60 subfamily.
限制条款
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