| 产品: | Hippocalcin 抗体 |
| 货号: | DF13752 |
| 描述: | Rabbit polyclonal antibody to Hippocalcin |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 22kDa, 18 kDa; 22kD(Calculated). |
| 蛋白号: | P84074 |
| RRID: | AB_2846771 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13752, RRID:AB_2846771.
展开/折叠
BDR 2; BDR2; Calcium binding protein BDR 2; Calcium binding protein BDR2; Calcium-binding protein BDR-2; HPCA; HPCA_HUMAN; Neuron specific calcium binding protein hippocalcin; Neuron-specific calcium-binding protein hippocalcin; P23K;
抗原和靶标
- P84074 HPCA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (By similarity).
Myristoylation facilitates association with membranes.
Cytoplasm>Cytosol. Membrane>Peripheral membrane protein.
Note: Association with membranes is calcium-dependent (By similarity). Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (PubMed:28398555).
Brain specific.
Oligomer; oligomerization is calcium-dependent. May interact with the voltage-dependent P/Q- and N-type calcium channels CACNA1A and CACNA1B.
Binds 3 calcium via EF-hand domains. The cryptic EF-hand 1 does not bind calcium.
Belongs to the recoverin family.
限制条款
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