LOXL4 Antibody - #DF13661

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产品: LOXL4 抗体
货号: DF13661
描述: Rabbit polyclonal antibody to LOXL4
应用: WB IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: Q96JB6
RRID: AB_2846680

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
LOXL4 Antibody detects endogenous levels of total LOXL4.
RRID:
AB_2846680
引用格式: Affinity Biosciences Cat# DF13661, RRID:AB_2846680.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

4833426I20Rik; FLJ21889; LOX L4; LOXC; LOXL 4; LOXL4; LOXL4_HUMAN; Lysyl oxidase homolog 4; Lysyl oxidase like 4; Lysyl oxidase like protein 4; Lysyl oxidase related C; Lysyl oxidase related protein C; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C;

抗原和靶标

免疫原:

A synthesized peptide derived from human LOXL4, corresponding to a region within N-terminal amino acids.

基因/基因ID:
LOXL4(84171)

文献引用

1). Deficiency of Integrin β 4 Results in Increased Lung Tissue Stiffness and Responds to Substrate Stiffness via Modulating RhoA Activity. Frontiers in cell and developmental biology, 2022 (PubMed: 35309934) [IF=4.6]

Application: IHC    Species: Mouse    Sample:

FIGURE 3. The expression of collagens, elastin and LOXs between ITGB4f/f and ITGB4ccsp.cre mice. (A,B) Masson’s Trichrome stain image (a, b) and ImageJ Imaging Software-generated image (c, d) to calculate Area % of collagen (Red). Scale bars: 50 μm. (C,D) The mRNA expression levels of collagens, elastin and LOXs were detected by RT-PCR. (E) Immunostaining for LOXL4 in airway epithelium (a,b) and alveolar septa (c,d) in ITGB4f/fand ITGB4ccsp.crelungs. Scale bars: 50 μm for (a, b);20 μm for (c, d). (F) Immunostaining for COLVI in pulmonary alveoli (a–d) and in airway epithelium (e–h) in ITGB4f/f and ITGB4ccsp.crelungs. Scale bars: 200 μm for (a, b, e, f); 50 μm for (c, d, g, h). (G) Immunostaining for elastin in pulmonary alveoli. Scale bars: 20 μm. (n = 3 independent experiments, *p < 0.05, **p < 0.01). Data are presented as mean ± SD.

Application: IF/ICC    Species: Mouse    Sample:

FIGURE 4. The expression of LOXL4,ColⅥ and elastin between ITGB4f/f and. ITGB4ccsp.cre mice (A) Immunofluorescence images of Col VI (green) and LOXL4 (pink) in the airway epithelium (a, b) and the Col VI (green) and elastin (red) in alveoli (c, d). Scale bars: 50 μm. (B) Immunofluorescence images of elastin in the in alveoli. Scale bars: 20 μm. Lung elastin accumulation (arrows) was distinctly greater in the ITGB4ccsp.cre lungs.
2). Pathological changes and expression of lysine oxidases and matrix metalloproteinases‐1,‐2, and‐3 in ligaments of patients with haemophilic arthritis. HAEMOPHILIA, 2022 (PubMed: 34697874) [IF=3.0]

Application: WB    Species: human    Sample: cruciate ligaments

Figure 5.|LOXs and MMP-1,-2,and -3protein expression levels in the cruciate ligaments of patients with OA or HA

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