CBX4 Antibody - #DF13461

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产品: CBX4 抗体
货号: DF13461
描述: Rabbit polyclonal antibody to CBX4
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat, Monkey
预测: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: O00257
RRID: AB_2846480

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
CBX4 Antibody detects endogenous levels of total CBX4.
RRID:
AB_2846480
引用格式: Affinity Biosciences Cat# DF13461, RRID:AB_2846480.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CBX 4; CBX4; Cbx4 chromobox homolog 4 (Drosophila Pc class); CBX4_HUMAN; Chromobox homolog 4 (Pc class homolog, Drosophila); Chromobox homolog 4; Chromobox protein homolog 4; E3 SUMO protein ligase CBX 4; E3 SUMO protein ligase CBX4; E3 SUMO-protein ligase CBX4; hPc 2; hPc2; NBP 16; NBP16; NS5ATP1 binding protein 16; Pc 2; Pc class 2 homolog; Pc class homolog; Pc class homolog Drosophila; PC2; Polycomb 2 homolog;

抗原和靶标

免疫原:

A synthesized peptide derived from human CBX4, corresponding to a region within the internal amino acids.

基因/基因ID:
CBX4(8535)

文献引用

1). METTL3 Promotes Osteosarcoma Metastasis via an m6A-dependent Epigenetic Activity of CBX4. Frontiers in bioscience (Landmark edition), 2024 (PubMed: 38538251) [IF=3.3]

Application: WB    Species: human    Sample: HOS cells and MG-63 cells

Fig. 5. CBX4 deficiency inhibits the metastasis of osteosarcoma cells. (A,B) Lentiviral transduction was used to interfere with CBX4 expression in HOS cells and MG-63 cells. (C) The migration ability was determined using the indicated stable cells as described in the Methods section. The results showed that silencing CBX4 significantly inhibited the metastasis of osteosarcoma cells (HOS cells and MG-63 cells). The results are expressed as the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 using two-tailed Student’s t test.

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