产品: FOXA2 抗体
货号: DF13363
描述: Rabbit polyclonal antibody to FOXA2
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: Q9Y261
RRID: AB_2846382

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   规格 价格 库存
 50ul RMB¥ 1500 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
FOXA2 Antibody detects endogenous levels of total FOXA2.
RRID:
AB_2846382
引用格式: Affinity Biosciences Cat# DF13363, RRID:AB_2846382.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Forkhead box A2; Forkhead box protein A2; FOX A2; foxa2; FOXA2_HUMAN; Hepatic nuclear factor 3 beta; Hepatocyte nuclear factor 3; Hepatocyte nuclear factor 3 beta; Hepatocyte nuclear factor 3-beta; HNF 3B; HNF-3-beta; HNF-3B; HNF3B; MGC19807; TCF 3B; TCF-3B; TCF3B; Transcription factor 3B;

抗原和靶标

免疫原:

A synthesized peptide derived from human FOXA2, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Human Diseases > Endocrine and metabolic diseases > Maturity onset diabetes of the young.

· Organismal Systems > Aging > Longevity regulating pathway - multiple species.   (View pathway)

文献引用

1). Foxa2 attenuates steatosis and inhibits the NF-κB/IKK signaling pathway in nonalcoholic fatty liver disease. PeerJ, 2023 (PubMed: 38084145) [IF=2.3]

Application: WB    Species: Mouse    Sample:

Figure 1 Forkhead box a2 (Foxa2) expression is decreased in nonalcoholic fatty liver disease (NAFLD) mice. (A) Body- and liver- weight and the ratio of body/liver weight. (B) Fasting blood glucose (FBG). (C) Protein expression of Foxa2 in liver tissues of each group of mice. C57BL/6 mice were fed with normal diet and high-fat diet (HFD) for eight weeks. Then, HFD mice were injected with overexpression negative control (oe-NC) and Foxa2 (oe-Foxa2) in the tail vein once every two weeks for four weeks. *P < 0.05 and **P < 0.01 compared with Control; #P < 0.05 and ##P < 0.01 compared with HFD.

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