FKBP51 Antibody - #DF13305

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产品: FKBP51 抗体
货号: DF13305
描述: Rabbit polyclonal antibody to FKBP51
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Zebrafish, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: Q13451
RRID: AB_2846324

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   规格 价格 库存
 50ul RMB¥ 1500 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
FKBP51 Antibody detects endogenous levels of total FKBP51.
RRID:
AB_2846324
引用格式: Affinity Biosciences Cat# DF13305, RRID:AB_2846324.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

51 kDa FK506 binding protein 5; 51 kDa FK506 binding protein; 51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor associated immunophilin; 54 kDa progesterone receptor-associated immunophilin; AIG 6; AIG6; Androgen regulated protein 6; Androgen-regulated protein 6; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP 5; FKBP 51; FKBP 54; FKBP-5; FKBP-51; FKBP5; FKBP5_HUMAN; FKBP54; HSP90 binding immunophilin; HSP90-binding immunophilin; MGC111006; OTTHUMP00000016268; P54; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; Peptidylprolyl cis trans isomerase; PPIase; PPIase FKBP5; Ptg 10; Ptg10; Rotamase; T cell FK506 binding protein;

抗原和靶标

免疫原:

A synthesized peptide derived from human FKBP51, corresponding to a region within the internal amino acids.

基因/基因ID:
FKBP5(2289)

研究领域

· Organismal Systems > Endocrine system > Estrogen signaling pathway.   (View pathway)

文献引用

1). Rosmarinic acid alleviate CORT-induced depressive-like behavior by promoting neurogenesis and regulating BDNF/TrkB/PI3K signaling axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2024 (PubMed: 38070249) [IF=6.9]

Application: WB    Species: Mouse    Sample:

Fig. 3. Effect of RA on the HPA axis and hippocampus region glucocorticoid-related proteins expression in chronic CORT injection depression model mice. (A) The levels of CORT in the serum (n = 6). (B) The levels of ACTH in the serum (n = 6). (C) The levels of CRH in the serum (n = 6). (D) Representative protein bands of glucocorticoid pathway (FKBP51, SGK-1, p-GR, GR, HSP90) (n = 3) in the hippocampus of mice. Statistical graphs of relative protein expression of FKBP51 (E), ratio of p-GR(Ser211)/GR (F), relative protein expression of SGK-1 (G) and relative protein expression of HSP90 (H). Data were normalized to the control and presented as means ± SEM.
2). Novel immunosuppressive effect of FK506 by upregulation of PD‐L1 via FKBP51 in heart transplantation. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2022 (PubMed: 35801698) [IF=4.1]

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