SCXA Antibody - #DF13293

>>赠JD卡 进行中>>
(6)   (30)  
产品: SCXA 抗体
货号: DF13293
描述: Rabbit polyclonal antibody to SCXA
应用: WB IHC
文献验证: WB, IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse
分子量: 21kDa; 22kD(Calculated).
蛋白号: Q7RTU7
RRID: AB_2846312

浏览相似产品>>

   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
预测:
Pig(100%), Bovine(%), Horse(%)
克隆:
Polyclonal
特异性:
SCXA Antibody detects endogenous levels of total SCXA.
RRID:
AB_2846312
引用格式: Affinity Biosciences Cat# DF13293, RRID:AB_2846312.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Basic helix loop helix transcription factor scleraxis; Basic helix-loop-helix transcription factor scleraxis; bHLHa41; bHLHa48; Class A basic helix-loop-helix protein 41; Class A basic helix-loop-helix protein 48; scleraxis; scleraxis homolog A; SCX; SCX_HUMAN; SCXB;

抗原和靶标

免疫原:
Uniprot:

Q7RTU7(SCX_HUMAN) >>Visit HPA database.

基因/基因ID:
SCX(642658)
序列:
MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Efficient DNA binding requires dimerization with another bHLH protein. Dimerizes and binds the E-box consensus sequence with E12 (By similarity).

文献引用

1). Harnessing Mechanical Stress with Viscoelastic Biomaterials for Periodontal Ligament Regeneration. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024 (PubMed: 38460171) [IF=15.1]
2). An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment. Acta Biomaterialia, 2025 [IF=9.6]
3). Small extracellular vesicles derived from tendon stem cells promote the healing of injured Achilles tendons by regulating miR-145-3p. Acta biomaterialia, 2023 (PubMed: 37806377) [IF=9.4]
4). Adipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3. Stem Cell Research & Therapy, 2021 (PubMed: 34112236) [IF=7.5]

Application: IHC    Species: rat    Sample: tendon

Fig. 5 |ADSC-Exos improved the healing of tendon injury. a, h The H&E staining of tendon injury at week 2 and week 4. b–f, i–m The expression of TNMD, collagen I, SCXA, ALP, and Runx2 were detected by immunohistochemistry assay at week 2 (n = 6) and week 4 (n = 6).
5). Biological Augmentation Using Electrospun Constructs with Dual Growth Factor Release for Rotator Cuff Repair. ACS applied bio materials, 2025 (PubMed: 40012485) [IF=4.6]
6). Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo. Oxidative Medicine and Cellular Longevity, 2022 (PubMed: 35178155)

Application: WB    Species: Rat    Sample: TSCs

Figure 3 EUG-BMSC-EVs protected tenogenic differentiation of H2O2-treated TSCs. (a–e) Western blot was used to examine the expression of SCXA, TNMD, TNC, and COLI. (f–i) The expression of tenocyte-related genes, SCX, TNMD, TNC, and Col1a1. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.