LOX Antibody - #DF13251

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产品: LOX 抗体
货号: DF13251
描述: Rabbit polyclonal antibody to LOX
应用: WB IHC IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
蛋白号: P28300
RRID: AB_2846270

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
LOX Antibody detects endogenous levels of total LOX.
RRID:
AB_2846270
引用格式: Affinity Biosciences Cat# DF13251, RRID:AB_2846270.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

lox; LYOX; LYOX_HUMAN; Lysyl oxidase; MGC105112; Protein lysine 6 oxidase; Protein-lysine 6-oxidase;

抗原和靶标

免疫原:

A synthesized peptide derived from human LOX, corresponding to a region within the internal amino acids.

基因/基因ID:
LOX(4015)

文献引用

1). Revealing the crosstalk between LOX+ fibroblast and M2 macrophage in gastric cancer by single-cell sequencing. BMC cancer, 2024 (PubMed: 39251966) [IF=3.8]

Application: IF/ICC    Species: human    Sample:

Fig. 7 The progression of gastric cancer is accelerated by LOX+ Fibroblasts and M2 Macrophages interactions. (A) Overall survival analyses for four subgroups of TCGA-STAD patients classified by the infiltration of both LOX+ Fibroblasts and M2 Macrophages. (B) GSEA of hypoxia, TNF BETA signaling, hypoxia, interferon response, and IL6-JAK-STAT3 pathways between LOX-fibroblasthigh/M2-macrophagehigh and LOX-fibroblastlow/M2-macrophagelow groups. Ranking genes by fold change in expression between these two conditions. NES, normalized enrichment score. (C) Comparison of the immune checkpoint expression level between LOX-fibroblasthigh/ M2-macrophagehigh and LOX-fibroblastlow/ M2-macrophagelow groups. (D) Characterization of cell location with mIHC. A staining panel was developed to visualize DAPI (blue), CD206(green) and LOX (red) simultaneously on the same tissue slide. Experiment was performed in two independent patients
2). Pathological changes and expression of lysine oxidases and matrix metalloproteinases‐1,‐2, and‐3 in ligaments of patients with haemophilic arthritis. HAEMOPHILIA, 2022 (PubMed: 34697874) [IF=3.0]

Application: WB    Species: human    Sample: cruciate ligaments

Figure 5.|LOXs and MMP-1,-2,and -3protein expression levels in the cruciate ligaments of patients with OA or HA

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