Neurofilament heavy polypeptide Antibody - #DF13211

Fig. 1 Peri-implant peripheral nerves. (A) NF histological examination of nerve fibers in the peri-implant bone revealed distinct patterns in the Control and T2DM groups. Representative images illustrate nerve fibers mainly distributed perivascularly and within bone tissue and a higher number of nerves around dental implants in the Control group compared to the T2DM group, where implants were often enveloped by connective tissue. (B) NPY histological analysis of nerve fibers in the peri-implant bone showed distinct differences between the Control and T2DM groups. Representative images demonstrated that nerve fibers were primarily located around blood vessels and within the bone tissue. The Control group exhibited a greater density of nerve fibers around dental implants compared to the T2DM group. (C) Nerve positive rate in the Control group was 80% which is significantly higher than the T2DM group’s 20%. (D) Immunofluorescence staining for CD63 in peri-implant bone tissue demonstrated the expression of CD63, a marker for exosomes. Notably, CD63 expression was observed in GFAP-positive cells, indicating that SCs were actively secreting exosomes in the peri-implant bone. T2DM: Type 2 diabetes mellitus, NF: Neurofilament, NPY: Neuropeptide Y, GFAP: glial fibrillary acidic protein, SCs: Schwann cells. *p 

Fig. 7. Neurofilament heavy polypeptide immunofluorescence staining of wound tissues. Detection of new neuron growth condition in the wound tissues of the control, CS, HUC-MSC + CS, and HUC-MSC EXO + CS groups on days 3, 7, 10, 14, and 16 by neurofilament heavy polypeptide immunofluorescence staining (magnification: 200×).