CDH2 Antibody - #BF9214

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产品: CDH2 抗体
货号: BF9214
描述: Mouse monoclonal antibody to CDH2
应用: WB IHC IF/ICC ELISA
反应: Human, Mouse, Rat
分子量: 99.8kDa; 89kD(Calculated).
蛋白号: Q9HBT6
RRID: AB_2846223

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
ELISA 1:10000, FCM (Flow Cytometric) 1:200-1:400, IF/ICC (Immunofluorescence Analysis) 1:200-1:1000, IHC (Immunohistochemical Analysis) 1:200-1:1000, WB (Western Blotting) 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Monoclonal [5D5]
特异性:
CDH2 antibody detects endogenous levels of total CDH2.
RRID:
AB_2846223
引用格式: Affinity Biosciences Cat# BF9214, RRID:AB_2846223.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Ascitic fluid containing 0.03% sodium azide. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Cadherin 20;Cadherin 20, type 2;Cdh7;CDH7L3;FLJ37047;

抗原和靶标

免疫原:

Purified recombinant fragment of human CDH2 expressed in E. Coli.

Uniprot:

Q9HBT6(CAD20_HUMAN) >>Visit HPA database.

基因/基因ID:
CDH20(28316)
表达:
Q9HBT6 CAD20_HUMAN:

Expressed in placenta, adult brain, and fetal brain.

序列:
MWTSGRMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASEGPAPLW

研究背景

功能:

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

细胞定位:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in placenta, adult brain, and fetal brain.

蛋白家族:

Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.

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