| 产品: | MDH2 抗体 |
| 货号: | DF13140 |
| 描述: | Rabbit polyclonal antibody to MDH2 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 33 kDa; 36kD(Calculated). |
| 蛋白号: | P40926 |
| RRID: | AB_2846100 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13140, RRID:AB_2846100.
展开/折叠
M MDH; Malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase; Malate dehydrogenase, mitochondrial; MDH; mdh2; MDHM_HUMAN; MGC:3559; mitochondrial; Mitochondrial malate dehydrogenase 2, NAD; Mor 1; MOR1;
抗原和靶标
- P40926 MDHM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P40926 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S18 | Phosphorylation | Uniprot | |
| S33 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| K74 | Acetylation | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| K78 | Acetylation | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| Y80 | Phosphorylation | Uniprot | |
| K91 | Acetylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K156 | Acetylation | Uniprot | |
| K157 | Acetylation | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| Y161 | Phosphorylation | Uniprot | |
| K165 | Acetylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| T171 | Phosphorylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| K203 | Acetylation | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| C212 | S-Nitrosylation | Uniprot | |
| T213 | Phosphorylation | Uniprot | |
| K215 | Acetylation | Uniprot | |
| T224 | Phosphorylation | Uniprot | |
| T227 | Phosphorylation | Uniprot | |
| T235 | Phosphorylation | Uniprot | |
| K239 | Acetylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| T248 | Phosphorylation | Uniprot | |
| Y253 | Phosphorylation | Uniprot | |
| R257 | Methylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| T283 | Phosphorylation | Uniprot | |
| C285 | S-Nitrosylation | Uniprot | |
| T286 | Phosphorylation | Uniprot | |
| Y287 | Phosphorylation | Uniprot | |
| K296 | Acetylation | Uniprot | |
| K296 | Ubiquitination | Uniprot | |
| K297 | Acetylation | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K301 | Acetylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| K307 | Acetylation | Uniprot | |
| K307 | Ubiquitination | Uniprot | |
| S310 | Phosphorylation | Uniprot | |
| K314 | Acetylation | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| K324 | Acetylation | Uniprot | |
| S326 | Phosphorylation | Uniprot | |
| K328 | Acetylation | Uniprot | |
| K329 | Acetylation | Uniprot | |
| K335 | Acetylation | Uniprot | |
| K335 | Ubiquitination | Uniprot | |
| T336 | Phosphorylation | Uniprot |
研究背景
Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri- and tetraacetylations. Glucose also increases acetylation by about 60%.
Mitochondrion matrix.
Homodimer.
Belongs to the LDH/MDH superfamily. MDH type 1 family.
研究领域
· Metabolism > Carbohydrate metabolism > Citrate cycle (TCA cycle).
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Carbohydrate metabolism > Glyoxylate and dicarboxylate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
限制条款
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