RCBTB1 Antibody - #AF0248

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产品: RCBTB1 抗体
货号: AF0248
描述: Rabbit polyclonal antibody to RCBTB1
应用: WB IHC IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 58kDa; 58kD(Calculated).
蛋白号: Q8NDN9
RRID: AB_2833423

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(92%), Horse(100%), Sheep(92%), Rabbit(92%), Dog(100%)
克隆:
Polyclonal
特异性:
RCBTB1 Antibody detects endogenous levels of total RCBTB1.
RRID:
AB_2833423
引用格式: Affinity Biosciences Cat# AF0248, RRID:AB_2833423.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; CLLL7; CLLL7 protein; E4.5; GDP/GTP exchange factor (GEF) like protein; GLP; Guanine nucleotide exchange factor; Hypothetical protein FLJ39335; RCBT1_HUMAN; Rcbtb1; RCC1 and BTB domain-containing protein 1; Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1; RP11-185C18.1;

抗原和靶标

免疫原:
Uniprot:

Q8NDN9(RCBT1_HUMAN) >>Visit HPA database.

基因/基因ID:
RCBTB1(55213)
表达:
Q8NDN9 RCBT1_HUMAN:

Ubiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781).

描述:
RCBTB1 May be involved in cell cycle regulation by chromatin remodeling. 2 isoforms of the human protein are produced by alternative splicing.
序列:
MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Dog
100
Bovine
92
Sheep
92
Rabbit
92
Xenopus
67
Zebrafish
67
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8NDN9 作为底物

Site PTM Type Enzyme
K67 Ubiquitination
K173 Ubiquitination
K283 Ubiquitination
K373 Ubiquitination
K379 Ubiquitination
K385 Ubiquitination
K464 Ubiquitination
K522 Ubiquitination
K525 Ubiquitination

研究背景

功能:

May be involved in cell cycle regulation by chromatin remodeling.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitously expressed. In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level).

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