产品: FMO5 抗体
货号: DF13018
描述: Rabbit polyclonal antibody to FMO5
应用: WB
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 60 kDa; 60kD(Calculated).
蛋白号: P49326
RRID: AB_2845979

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 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Zebrafish(83%), Bovine(92%), Horse(83%), Sheep(92%), Rabbit(92%), Dog(92%), Xenopus(92%)
克隆:
Polyclonal
特异性:
FMO5 Antibody detects endogenous levels of total FMO5.
RRID:
AB_2845979
引用格式: Affinity Biosciences Cat# DF13018, RRID:AB_2845979.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Dimethylaniline monooxygenase [N oxide forming] 5; Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; FMO 5; FMO5; FMO5_HUMAN; Hepatic flavin containing monooxygenase 5; Hepatic flavin-containing monooxygenase 5;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P49326 FMO5_HUMAN:

Expressed in fetal and adult liver.

序列:
MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Bovine
92
Sheep
92
Dog
92
Xenopus
92
Rabbit
92
Horse
83
Zebrafish
83
Chicken
75
Pig
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P49326 作为底物

Site PTM Type Enzyme
S54 Phosphorylation
Y56 Phosphorylation
S58 Phosphorylation
Y104 Phosphorylation
Y171 Phosphorylation
Y177 Phosphorylation
S280 Phosphorylation
T284 Phosphorylation
T398 Phosphorylation
S410 Phosphorylation
T501 Phosphorylation
S509 Phosphorylation
S512 Phosphorylation

研究背景

功能:

In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.

细胞定位:

Microsome membrane. Endoplasmic reticulum membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in fetal and adult liver.

蛋白家族:

Belongs to the FMO family.

研究领域

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

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