产品: FAM134B 抗体
货号: DF12997
描述: Rabbit polyclonal antibody to FAM134B
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
蛋白号: Q9H6L5
RRID: AB_2845958

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
FAM134B Antibody detects endogenous levels of total FAM134B.
RRID:
AB_2845958
引用格式: Affinity Biosciences Cat# DF12997, RRID:AB_2845958.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

F134B_HUMAN; FAM134B; family with sequence similarity 134 member B; HSAN2B; JK 1; JK1; Protein FAM134B;

抗原和靶标

免疫原:

A synthesized peptide derived from human FAM134B, corresponding to a region within the internal amino acids.

基因/基因ID:

文献引用

1). SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection. Autophagy, 2022 (PubMed: 35239449) [IF=14.6]

2). Physical exercise mitigates the cognitive impairments by promoting ER-phagy in mice model of Alzheimer's disease. Behavioural brain research, 2025 (PubMed: 40414310) [IF=2.6]

3). Sequential ER stress and inflammatory responses are induced by SARS-CoV-2 ORF3 through ERphagy. bioRxiv, 2020

Application: WB    Species: Human    Sample: HEK293T cells

Figure S2.ORF3 does not affect FAM134B expression Flag-ORF3 or empty vector was transfected into HEK293T cells. Thirty-six hours after transfection, cell pellets were collected, and the whole cell extracts were analyzed by Western blots to detect the level of FAM134B expression.

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