产品: DSN1 抗体
货号: DF12962
描述: Rabbit polyclonal antibody to DSN1
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Dog
分子量: 40 kDa; 40kD(Calculated).
蛋白号: Q9H410
RRID: AB_2845923

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
预测:
Pig(82%), Dog(%)
克隆:
Polyclonal
特异性:
DSN1 Antibody detects endogenous levels of total DSN1.
RRID:
AB_2845923
引用格式: Affinity Biosciences Cat# DF12962, RRID:AB_2845923.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C20orf172; Chromosome 20 open reading frame 172; dJ469A13.2; DSN1; DSN1, MIND kinetochore complex component, homolog; DSN1, MIND kinetochore complex component, homolog (S. cerevisiae); DSN1, MIS12 kinetochore complex component; DSN1_HUMAN; FLJ13346; hKNL-3; Kinetochore associated protein DSN1; Kinetochore associated protein DSN1 homolog; Kinetochore null 3 homolog; Kinetochore-associated protein DSN1 homolog; KNL3; MGC32987; MIS13;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MTSVTRSEIIDEKGPVMSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQ

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Dog
90
Pig
82
Horse
73
Bovine
64
Sheep
64
Rabbit
64
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.

细胞定位:

Nucleus. Chromosome>Centromere>Kinetochore.
Note: Associated with the kinetochore.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3 and CBX5. Interacts with KNSTRN.

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