| 产品: | C7orf30 抗体 |
| 货号: | DF12871 |
| 描述: | Rabbit polyclonal antibody to C7orf30 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Pig, Rabbit, Dog |
| 分子量: | 26 kDa; 26kD(Calculated). |
| 蛋白号: | Q96EH3 |
| RRID: | AB_2845832 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12871, RRID:AB_2845832.
展开/折叠
C7orf30; CG030_HUMAN; Chromosome 7 open reading frame 30; Uncharacterized protein C7orf30;
抗原和靶标
- Q96EH3 MASU1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGPGGRVARLLAPLMWRRAVSSVAGSAVGAEPGLRLLAVQRLPVGAAFCRACQTPNFVRGLHSEPGLEERAEGTVNEGRPESDAADHTGPKFDIDMMVSLLRQENARDICVIQVPPEMRYTDYFVIVSGTSTRHLHAMAFYVVKMYKHLKCKRDPHVKIEGKDTDDWLCVDFGSMVIHLMLPETREIYELEKLWTLRSYDDQLAQIAPETVPEDFILGIEDDTSSVTPVELKCE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. May function as a ribosomal silencing factor (Probable).
Mitochondrion matrix.
Note: Colocalizes with MRPL12 and/or MRPL14.
Associates with the mitochondrial ribosome large subunit (39S) via interaction with MRPL12 and/or MRPL14. The interaction generates steric hindrance that is expected to prevent premature association of the 28S and 39S ribosomal subunits. Intentified in a complex composed of MALSU1, MIEF1 upstream open reading frame protein and NDUFAB1; within the trimeric complex MIEF1 upstream open reading frame protein functions as a bridging scaffold that interacts with MALSU1 on one side, and with NDUFAB1 on the other side. Interacts with MRPL12 and MRPL14.
Belongs to the Iojap/RsfS family.
限制条款
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