| 产品: | PTPRR 抗体 |
| 货号: | DF12713 |
| 描述: | Rabbit polyclonal antibody to PTPRR |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 47 kDa; 74kD(Calculated). |
| 蛋白号: | Q15256 |
| RRID: | AB_2845674 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12713, RRID:AB_2845674.
展开/折叠
Ch-1PTPase; Ch1 PTPase; DKFZp781C1038; EC PTP; ECPTP; FLJ34328; MGC131968; MGC148170; NC PTPCOM1; NC-PTPCOM1; Protein tyrosine phosphatase Cr1PTPase precursor; Protein tyrosine phosphatase NC PTPCOM1; Protein tyrosine phosphatase PCPTP1; Protein tyrosine phosphatase receptor type R; Protein-tyrosine phosphatase PCPTP1; PTP SL; PTPBR7; PTPRQ; PTPRR; PTPRR_HUMAN; PTPSL; R-PTP-R; Receptor type tyrosine protein phosphatase R; Receptor-type tyrosine-protein phosphatase R;
抗原和靶标
Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
- Q15256 PTPRR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRRAVCFPALCLLLNLHAAGCFSGNNDHFLAINQKKSGKPVFIYKHSQDIEKSLDIAPQKIYRHSYHSSSEAQVSKRHQIVNSAFPRPAYDPSLNLLAMDGQDLEVENLPIPAANVIVVTLQMDVNKLNITLLRIFRQGVAAALGLLPQQVHINRLIGKKNSIELFVSPINRKTGISDALPSEEVLRSLNINVLHQSLSQFGITEVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
Cell membrane>Single-pass type I membrane protein.
Cytoplasm>Perinuclear region.
Note: Locates to the perinuclear areas within the cytoplasm.
Cytoplasm>Perinuclear region.
Note: Locates to the perinuclear areas within the cytoplasm.
Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
Interacts with MAPKs.
Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
研究领域
· Environmental Information Processing > Signal transduction > MAPK signaling pathway. (View pathway)
限制条款
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