IRF1 Antibody - #DF12645

>>买2送1 进行中>>
>>赠JD卡 进行中>>
(1)   (5)  
产品: IRF1 抗体
货号: DF12645
描述: Rabbit polyclonal antibody to IRF1
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: P10914
RRID: AB_2845607

浏览相似产品>>

   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
IRF1 Antibody detects endogenous levels of total IRF1.
RRID:
AB_2845607
引用格式: Affinity Biosciences Cat# DF12645, RRID:AB_2845607.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Interferon regulatory factor 1; Interferon regulatory factor 1 isoform +I9; Interferon regulatory factor 1 isoform d78; Interferon regulatory factor 1 isoform delta4; Interferon regulatory factor 1 isoform delta7; IRF 1; IRF-1; IRF1; IRF1_HUMAN; MAR; MAR1;

抗原和靶标

免疫原:

A synthesized peptide derived from human IRF1, corresponding to a region within the internal amino acids.

基因/基因ID:
IRF1(3659)

研究领域

· Human Diseases > Infectious diseases: Bacterial > Pertussis.

· Human Diseases > Infectious diseases: Viral > Hepatitis C.

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Organismal Systems > Endocrine system > Prolactin signaling pathway.   (View pathway)

文献引用

1). IRF-1 contributes to the pathological phenotype of VSMCs during atherogenesis by increasing CCL19 transcription. Aging-US, 2021 (PubMed: 33424012) [IF=3.9]

Application: WB    Species: Human    Sample: VSMCS

Figure 5 Effects of IRF-1 on VSMCS though CCL19. (A) Detection of overexpression efficiency of IRF-1 plasmid by qRT-PCR. n=5. Knockdown CCL19 reversed IRF-1 induced mRNA expression of inflammatory cytokine IL1-α (B), IL-1β (C), TNF-α (D), IL-6 (E) and the deposition of ECM collagen1 (F), collagen3 (G) and OPN. (H, I) Western blot showed the collagen1, IL-6 and CCL19 protein expression induced by IRF-1, but reduced by sh-CCL19. n = 4. Migration (J) and proliferation (K) of VSMCS of IRF-1 overexpression, with or without sh-CCL19. n = 6. *P<0.05; **P<0.01.

Application: IF/ICC    Species: Human    Sample: VSMCS

Figure 5 Effects of IRF-1 on VSMCS though CCL19. (A) Detection of overexpression efficiency of IRF-1 plasmid by qRT-PCR. n=5. Knockdown CCL19 reversed IRF-1 induced mRNA expression of inflammatory cytokine IL1-α (B), IL-1β (C), TNF-α (D), IL-6 (E) and the deposition of ECM collagen1 (F), collagen3 (G) and OPN. (H, I) Western blot showed the collagen1, IL-6 and CCL19 protein expression induced by IRF-1, but reduced by sh-CCL19. n = 4. Migration (J) and proliferation (K) of VSMCS of IRF-1 overexpression, with or without sh-CCL19. n = 6. *P<0.05; **P<0.01.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.