GSTA2 Antibody - #DF12623

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产品: GSTA2 抗体
货号: DF12623
描述: Rabbit polyclonal antibody to GSTA2
应用: WB
反应: Human, Mouse, Rat
分子量: 26 kDa; 26kD(Calculated).
蛋白号: P09210
RRID: AB_2845585

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
GSTA2 Antibody detects endogenous levels of total GSTA2.
RRID:
AB_2845585
引用格式: Affinity Biosciences Cat# DF12623, RRID:AB_2845585.
偶联:
Unconjugated. 130
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

EC 2.5.1.18; Glutathione S transferase 2; Glutathione S transferase A2; Glutathione S-alkyltransferase A2; Glutathione S-aralkyltransferase A2; Glutathione S-aryltransferase A2; Glutathione S-transferase alpha 2; Glutathione S-transferase GT41A; Glutathione S-transferase Ya-2; Glutathione S-transferase, alpha 2 (Yc2); GST 1b-1b; GST A2-2; GST class alpha member 2; GST gamma; GST HA subunit 2; GST Ya2; GST, class alpha, 2; GST2; Gst2-2; GSTA2 2; GSTA2-2; Gstc-2; Gstc2; GTA2; GTH2; HA subunit 2; Liver GST2; MGC10525; OTTHUMP00000017883; S-(hydroxyalkyl)glutathione lyase A2;

抗原和靶标

免疫原:
Uniprot:

P09210(GSTA2_HUMAN) >>Visit HPA database.

基因/基因ID:
GSTA2(2939)
表达:
P09210 GSTA2_HUMAN:

Liver.

序列:
MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF

研究背景

功能:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Liver.

亚基结构:

Homodimer or heterodimer of GSTA1 and GSTA2.

蛋白家族:

Belongs to the GST superfamily. Alpha family.

研究领域

· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma.   (View pathway)

· Metabolism > Metabolism of other amino acids > Glutathione metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.

文献引用

1). Transcriptomics and metabolomics reveal the role of CYP1A2 in psoralen/isopsoralen-induced metabolic activation and hepatotoxicity. Phytotherapy Research, 2023 (PubMed: 36056681) [IF=6.1]

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