| 产品: | GGCX 抗体 |
| 货号: | DF12616 |
| 描述: | Rabbit polyclonal antibody to GGCX |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 88 kDa; 88kD(Calculated). |
| 蛋白号: | P38435 |
| RRID: | AB_2845578 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12616, RRID:AB_2845578.
展开/折叠
FLJ26629; Gamma glutamyl carboxylase; Gamma-glutamyl carboxylase; GC; GGCX; Peptidyl glutamate 4 carboxylase; Peptidyl-glutamate 4-carboxylase; Vitamin K dependent gamma carboxylase; Vitamin K gamma glutamyl carboxylase; Vitamin K-dependent gamma-carboxylase; VKCFD 1; VKCFD1; VKGC_HUMAN;
抗原和靶标
- P38435 VKGC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAVSAGSARTSPSSDKVQKDKAELISGPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDALRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLLNAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSAGFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYKRSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYLNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLLMDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEYHKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRLQEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNPPESNPDPVHSEF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P38435 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S7 | Phosphorylation | Uniprot | |
| T10 | Phosphorylation | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| K16 | Ubiquitination | Uniprot | |
| K19 | Acetylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| S26 | Phosphorylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| K334 | Ubiquitination | Uniprot | |
| K346 | Ubiquitination | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| K438 | Ubiquitination | Uniprot | |
| K445 | Ubiquitination | Uniprot | |
| N459 | N-Glycosylation | Uniprot | |
| K515 | Ubiquitination | Uniprot | |
| N550 | N-Glycosylation | Uniprot | |
| K578 | Ubiquitination | Uniprot | |
| S695 | Phosphorylation | Uniprot |
研究背景
Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Monomer. May interact with CALU (By similarity).
Belongs to the vitamin K-dependent gamma-carboxylase family.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Ubiquinone and other terpenoid-quinone biosynthesis.
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