TM158 Antibody - #DF12531

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产品: TM158 抗体
货号: DF12531
描述: Rabbit polyclonal antibody to TM158
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse
预测: Pig, Bovine, Chicken
蛋白号: Q8WZ71
RRID: AB_2845493

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
TM158 Antibody detects endogenous levels of total TM158.
RRID:
AB_2845493
引用格式: Affinity Biosciences Cat# DF12531, RRID:AB_2845493.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

40 kDa BINP binding protein; 40 kDa BINP-binding protein; BBP; BINP receptor; Brain injury derived neurotrophic peptide (BINP) binding protein; Brain specific binding protein; DKFZp586E1621; HBBP; p40BBP; Ras induced senescence protein 1; Ras-induced senescence protein 1; RIS1; TM158_HUMAN; TMEM 158; TMEM158; Transmembrane protein 158;

抗原和靶标

免疫原:

A synthesized peptide derived from human TM158, corresponding to a region within the internal amino acids.

基因/基因ID:
TMEM158(25907)

文献引用

1). TMEM158 functions as an oncogene and promotes lung adenocarcinoma progression through the PI3K/AKT pathway via interaction with TWIST1. Experimental cell research, 2024 (PubMed: 38508329) [IF=3.3]

Application: WB    Species: human    Sample:

Fig. 1. Expression patterns of TMEM158 in LUAD patients. (A, B) Volcano plots depicting the DEGs in LUAD were generated utilizing both TCGA-LUAD and GSE140797 datasets. (C) The Venn diagram illustrated the overlapping DEGs between the TCGA-LUAD and GSE140797 datasets. (D, E) In the TCGA-LUAD dataset, TMEM158 expression revealed a significant increase in LUAD tissues in comparison with healthy tissues. (F) The analysis of the GSE140797 dataset has shown that TMEM158 expression is raised in LUAD tissues contrasted to normal tissues. (G) Expression of TMEM158 in different malignancy kinds was analyzed employing data acquired from the TCGA database. (H, I) Analysis of LUAD samples and nearby normal tissues was conducted utilizing western blotting and qRT–PCR. *p < 0.05; **p < 0.01; ***p < 0.001.

Application: IHC    Species: human    Sample: H1650 cells

Fig. 4. TMEM158 promotes migration and invasion while inhibiting cell apoptosis in LUAD cells. (A, B) The apoptotic activities of H1650 cells were assessed using flow cytometry. (C, D) The migratory capability of H1650 cells was assessed employing the wound healing assay. (E, F) The Transwell invasion assay was employed to assess the invasiveness of H1650 cells. *p < 0.05.

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