Phospho-AS160 (Ser318) Antibody - #AF2317

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产品: 磷酸化 AS160 (Ser318) 抗体
货号: AF2317
描述: Rabbit polyclonal antibody to Phospho-AS160 (Ser318)
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: O60343
RRID: AB_2845331

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Phospho-AS160 (Ser318) Antibody detects endogenous levels of AS160 only when phosphorylated at Ser318.
RRID:
AB_2845331
引用格式: Affinity Biosciences Cat# AF2317, RRID:AB_2845331.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Acrg embryonic lethality (mouse) minimal region ortholog; Acrg embryonic lethality minimal region ortholog; Acrg embryonic lethality mouse minimal region ortholog; Akt substrate of 160 kDa; AS 160; AS160; BUB2; CDC16; KIAA0603; NIDDM5; TBC (Tre 2 BUB2 CDC16) domain containing protein; TBC Tre 2 BUB2 CDC16 domain containing protein; TBC1 D4; TBC1 domain family member 4; Tbc1d4; TBCD4_HUMAN; Tre-2;

抗原和靶标

免疫原:

A synthesized peptide derived from human AS160 around the phosphorylation site of Ser318.

基因/基因ID:
TBC1D4(9882)

研究领域

· Human Diseases > Endocrine and metabolic diseases > Insulin resistance.

· Organismal Systems > Endocrine system > Thyroid hormone signaling pathway.   (View pathway)

文献引用

1). Akt Phosphorylation Influences Persistent Chlamydial Infection and Chlamydia-Induced Golgi Fragmentation Without Involving Rab14. Frontiers in Cellular and Infection Microbiology, 2021 (PubMed: 34169005) [IF=4.6]
2). Central GLP-1 contributes to improved cognitive function and brain glucose uptake after duodenum-jejunum bypass on obese and diabetic rats. American Journal of Physiology-Endocrinology and Metabolism, 2021 (PubMed: 34370593) [IF=4.2]

Application: WB    Species: Rat    Sample: brain

Figure 9. The effect of glucagon-like peptide-1 (GLP-1) receptor (Glp-1r) knockdown (KD) on brain glucose uptake and validation of Glp-1r KD. A and B: representative rat brain positron emission tomography (PET) images and comparisons on the glucose uptake of the whole brain on each hemicerebrum among subgroups. C: immunoblotting of brain GLP-1R in different regions. D: immunoblotting of glucose uptake-related proteins. Multiple comparisons in two-way ANOVA were used, and data are expressed as means ± SD. ****P < 0.0001 (n = 4 for animals in each group). AS160, Akt substrate of 160 kDa; DJB, duodenum-jejunum bypass; GLUT, glucose transporter; SUV, standardized uptake value.
3). Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1. Biochemistry (Moscow), 2020 (PubMed: 32564738) [IF=2.3]

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