产品: | Pax-5 抗体 |
货号: | AF0238 |
描述: | Rabbit polyclonal antibody to Pax-5 |
应用: | WB IF/ICC |
反应: | Human, Mouse |
预测: | Pig, Horse, Rabbit, Dog |
分子量: | 40kDa; 42kD(Calculated). |
蛋白号: | Q02548 |
RRID: | AB_2833413 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0238, RRID:AB_2833413.
展开/折叠
B cell lineage specific activator; B cell lineage specific activator protein; B cell specific activator protein; B cell specific transcription factor; B-cell-specific transcription factor; BSAP; EBB-1; KLP; Paired box 5; Paired box gene 5 (B cell lineage specific activator protein); Paired box gene 5 (B cell lineage specific activator); Paired box gene 5; Paired box homeotic gene 5; Paired box protein Pax 5; Paired box protein Pax-5; Paired domain gene 5; PAX 5; PAX5; PAX5_HUMAN; Transcription factor PAX 5;
抗原和靶标
- Q02548 PAX5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q02548 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T9 | Phosphorylation | Uniprot | |
T15 | Phosphorylation | Uniprot | |
Y102 | Phosphorylation | Uniprot | |
S133 | Phosphorylation | Uniprot | |
S168 | Phosphorylation | Uniprot | |
Y179 | Phosphorylation | Uniprot | |
S180 | Phosphorylation | Uniprot | |
S206 | Phosphorylation | Uniprot | |
S298 | Phosphorylation | Uniprot | |
Y299 | Phosphorylation | Uniprot | |
R377 | Methylation | Uniprot |
研究背景
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
O-glycosylated.
Nucleus.
Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4. Interacts with ETS1, altering its DNA-binding properties.
研究领域
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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