产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12132, RRID:AB_2844937.
展开/折叠
EC 2.6.1.52; Endometrial progesterone induced protein; EPIP; MGC1460; NLS2; Phosphohydroxythreonine aminotransferase; phosphoserine aminotransferase 1; Phosphoserine aminotransferase; PSA; PSAT; Psat1; PSATD; SERC_HUMAN;
抗原和靶标
Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
- Q9Y617 SERC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSKMNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQKLAAFMKKFLEMHQL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y617 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| R5 | Methylation | Uniprot | |
| K16 | Ubiquitination | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| K27 | Ubiquitination | Uniprot | |
| Y32 | Phosphorylation | Uniprot | |
| K33 | Ubiquitination | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| R45 | Methylation | Uniprot | |
| K51 | Acetylation | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| R97 | Methylation | Uniprot | |
| C98 | S-Nitrosylation | Uniprot | |
| K110 | Acetylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| K127 | Acetylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| R222 | Methylation | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| K269 | Acetylation | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| K274 | Ubiquitination | Uniprot | |
| Y279 | Phosphorylation | Uniprot | |
| K300 | Ubiquitination | Uniprot | |
| K311 | Acetylation | Uniprot | |
| K311 | Ubiquitination | Uniprot | |
| K318 | Acetylation | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| K323 | Acetylation | Uniprot | |
| K323 | Ubiquitination | Uniprot | |
| S331 | Phosphorylation | Uniprot | |
| K333 | Acetylation | Uniprot | |
| K333 | Methylation | Uniprot | |
| K333 | Ubiquitination | Uniprot | |
| R336 | Methylation | Uniprot | |
| S344 | Phosphorylation | Uniprot | |
| Y346 | Phosphorylation | Uniprot | |
| K356 | Ubiquitination | Uniprot | |
| K363 | Ubiquitination | Uniprot |
研究背景
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Homodimer.
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
研究领域
· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.
· Metabolism > Metabolism of cofactors and vitamins > Vitamin B6 metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
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