产品: MYH7 抗体
货号: DF12122
描述: Rabbit polyclonal antibody to MYH7
应用: WB IHC IF/ICC
文献验证: IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Dog
蛋白号: P12883
RRID: AB_2844927

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
MYH7 Antibody detects endogenous levels of total MYH7.
RRID:
AB_2844927
引用格式: Affinity Biosciences Cat# DF12122, RRID:AB_2844927.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Beta myosin heavy chain; cardiac muscle beta isoform; CMD1S; CMH1; MPD1; MYH7; MYH7_HUMAN; Myhc slow; MyHC-beta; MyHC-slow; MYHCB; Myopathy, distal 1; Myosin heavy chain (AA 1-96); Myosin heavy chain 7; Myosin heavy chain; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform; Myosin, heavy chain 7, cardiac muscle, beta; Myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-7; Rhabdomyosarcoma antigen MU RMS 40.7A; SPMD; SPMM;

抗原和靶标

免疫原:

A synthesized peptide derived from human MYH7, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Human Diseases > Cardiovascular diseases > Hypertrophic cardiomyopathy (HCM).

· Human Diseases > Cardiovascular diseases > Dilated cardiomyopathy (DCM).

· Human Diseases > Cardiovascular diseases > Viral myocarditis.

· Organismal Systems > Circulatory system > Cardiac muscle contraction.   (View pathway)

· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes.   (View pathway)

文献引用

1). Comparative Analysis of Muscle Fibers in Selected Muscles of Working and Companion Dog Breeds. Animals : an open access journal from MDPI, 2024 (PubMed: 39765480) [IF=3.0]

Application: IHC    Species: dog    Sample:

Figure 2. Immunohistochemical staining of muscle fibers in the triceps brachii of companion and working dog breeds, illustrating the distribution of different myosin heavy chain (MYH) isoforms. Staining was performed using DAB as a chromogen. The rows represent different myosin heavy chain isoforms, with MYH2, MYH4, and MYH7 detected in companion and working breeds. Arrows indicate immunoreactive muscle fibers displaying the respective MYH isoform. Scale bars are included in each image for reference (100 µm and 200 µm).

2). Development of CRISRP/Cas9-based TP53-knockout pig muscle stem cells for use in the cultured meat industry. 3 Biotech, 2025 (PubMed: 40115325) [IF=2.6]

3). Hoxa11 and Hoxa13 facilitate slow‐twitch muscle formation in C2C12 cells and indirectly affect the lipid deposition of 3T3‐L1 cells. ANIMAL SCIENCE JOURNAL, 2021 (PubMed: 33738916) [IF=1.7]

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