TET2 Antibody - #DF12089

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产品: TET2 抗体
货号: DF12089
描述: Rabbit polyclonal antibody to TET2
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: Q6N021
RRID: AB_2844894

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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实验方案
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
TET2 Antibody detects endogenous levels of total TET2.
RRID:
AB_2844894
引用格式: Affinity Biosciences Cat# DF12089, RRID:AB_2844894.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ20032; KIAA1546; MDS; Methylcytosine dioxygenase TET2; Nbla00191; Probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Tet 2; Tet methylcytosine dioxygenase 2; Tet oncogene 2; Tet oncogene family member 2; TET2; TET2_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human TET2, corresponding to a region within the internal amino acids.

基因/基因ID:
TET2(54790)

文献引用

1). Activation of prep expression by Tet2 promotes the proliferation of bipotential progenitor cells during liver regeneration. Development (Cambridge, England), 2025 (PubMed: 39976298) [IF=3.7]
2). CircDIP2C ameliorates oxidized low-density lipoprotein-induced cell dysfunction by binding to miR-556-5p to induce TET2 in human umbilical vein endothelial cells. VASCULAR PHARMACOLOGY, 2021 (PubMed: 34147657) [IF=3.5]

Application: WB    Species: Human    Sample: umbilical vein endothelial cells

Fig. 5. TET2 expression was modulated by circDIP2C through functioning as a target gene of miR-556-5p in HUVECs. (A) The binding sites between miR-556-5p and TET2 were predicted by targetscan database. (B-D) The binding relationship between miR-556-5p and TET2 was proved by dual-luciferase reporter, RIP and RNA pull-down assays in HUVECs. (E and F) The mRNA and protein expression of TET2 were detected by qRT-PCR or western blot analysis in the HUVECs transfected with miR-NC or miR-556-5p. (G and H) The effects between circDIP2C and miR-556-5p overexpression on the mRNA and protein expression of TET2 were determined by qRT-PCR or western blot analysis in HUVECs. (I and J) The impacts of ox-LDL on the mRNA and protein expression of TET2 were demonstrated by qRT-PCR and western blot analysis, respectively, in HUVECs. *P < 0.05.

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