产品: MER/TYRO3 抗体
货号: DF10363
描述: Rabbit polyclonal antibody to MER/TYRO3
应用: WB
文献验证: WB
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
蛋白号: Q12866 | Q06418
RRID: AB_2844370

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
MER/TYRO3 Antibody detects endogenous levels of total MER/TYRO3.
RRID:
AB_2844370
引用格式: Affinity Biosciences Cat# DF10363, RRID:AB_2844370.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

c MER; c mer proto oncogene tyrosine kinase; c-mer; cMER; cmer protooncogene tyrosine kinase; Eyk; MER; MER receptor tyrosine kinase; MERK; MERPEN; Mertk; MERTK c-mer proto-oncogene tyrosine kinase; MERTK_HUMAN; MGC133349; nmf12; Nyk; Proto oncogene tyrosine protein kinase MER; Proto oncogene tyrosine protein kinase MER precursor; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; RP38; STK kinase; Tyrosine-protein kinase Mer; Brt; BYK; DTK; Etk-2; protein tyrosine kinase 3; Rek; RSE; SKY; Tif; tyro3; TYRO3 protein tyrosine kinase; TYRO3_HUMAN; Tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF;

抗原和靶标

免疫原:

A synthesized peptide derived from human MER/TYRO3, corresponding to a region within the internal amino acids.

基因/基因ID:

文献引用

1). LGR6 modulates intervertebral disc degeneration through regulation of macrophage efferocytosis. Journal of translational medicine, 2025 (PubMed: 40281518) [IF=7.4]

2). Gas6 Attenuates Sepsis-Induced Tight Junction Injury and Vascular Endothelial Hyperpermeability via the Axl/NF-κB Signaling Pathway. Frontiers in Pharmacology, 2019 (PubMed: 31263416) [IF=5.6]

Application: WB    Species: Mouse    Sample: MAECs

Figure 5 TAM receptor expression in MAECs and Axl siRNA transfection efficiency. (A, C) Western blotting analysis of the expression of TAM receptors (Tyro3, Axl, and Mertk) in MACEs (n = 3, means ± SD). (B, D) Axl was activated when MAECs were incubated with Gas6; Western blotting was used to examine the Axl phosphorylation expression (n = 3, means ± SD, **P < 0.01 versus the control group). (E, F) MAECs were transfected with Axl siRNA (siAxl) or nonspecific control siRNA (siNC) for 36 h; Western blotting was used to examine the protein expression of Axl after MAECs transfected with siAxl. β-Actin was used as the loading control and for band density normalization (n = 3, mean ± SD, **P < 0.01 versus the siNC group).

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