产品: TBC1D1 抗体
货号: AF7908
描述: Rabbit polyclonal antibody to TBC1D1
应用: WB
文献验证: WB
反应: Human, Mouse
分子量: 133kDa;
蛋白号: Q60949
RRID: AB_2819093

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
TBC1D1 Antibody detects endogenous levels of total TBC1D1.
RRID:
AB_2819093
引用格式: Affinity Biosciences Cat# AF7908, RRID:AB_2819093.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

KIAA1108; TBC 1; TBC; TBC1 (tre 2/USP6, BUB2, cdc16) domain family, member 1; TBC1; TBC1 domain family member 1; Tbc1d1; TBCD1_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from mouse TBC1D1, corresponding to a region within the internal amino acids.

文献引用

1). HWL-088, a new highly potent FFAR1 agonist, improves glucolipid metabolism and acts additively with Metformin in ob/ob diabetic mice. BRITISH JOURNAL OF PHARMACOLOGY, 2020 (PubMed: 31971610) [IF=6.8]

Application: WB    Species: mice    Sample: liver

FIGURE 4 Effects of HWL-088 on plasma glucose levels (a) and corresponding AUC0–90min (b) of glucose during an OGTT in fasting ob/ob mice. Tested agents or vehicle was orally administered to ob/ob mice twice daily for 30 days, and the OGTTs were determined on treatment days 1, 15, and 30. After long-term treatment, hepatic expression of genes involved in gluconeogenesis (c) and glycogen synthesis (d) as well as hepatic expression of GSK3β (e). Effects of HWL-088 on the phosphorylation of AKT, AS160, and TBC1D1 in L6 myoblasts cells (f). Values are mean ± SD (n = 6). *P ≤ .05 was analysed using a one-way ANOVA with Tukey's multiple-comparison post hoc test

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