FGFR4 Antibody - #AF7762

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产品: FGFR4 抗体
货号: AF7762
描述: Rabbit polyclonal antibody to FGFR4
应用: WB
文献验证: WB
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: P22455
RRID: AB_2844126

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
FGFR4 Antibody detects endogenous levels of total FGFR4.
RRID:
AB_2844126
引用格式: Affinity Biosciences Cat# AF7762, RRID:AB_2844126.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CD 334; CD334; CD334 antigen; fc13h 10; fc13h10; Fgfr 4; FGFR-4; Fgfr4; FGFR4_HUMAN; Fibroblast growth factor receptor 4; Hydroxyaryl protein kinase; JTK 2; JTK2; MGC20292; Protein tyrosine kinase; TKF; Tyrosine kinase related to fibroblast growth factor receptor; Tyrosylprotein kinase;

抗原和靶标

免疫原:

A synthesized peptide derived from human FGFR4, corresponding to a region within the internal amino acids.

基因/基因ID:
FGFR4(2264)

研究领域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells.   (View pathway)

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

· Environmental Information Processing > Signal transduction > MAPK signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

文献引用

1). Fibroblast Growth Factor Receptor 4 Promotes Triple-Negative Breast Cancer Progression via Regulating Fatty Acid Metabolism Through the AKT/RYR2 Signaling. Cancer medicine, 2024 (PubMed: 39658878) [IF=2.9]
2). miR-7-5p Promotes Hepatic Stellate Cell Activation by Targeting Fibroblast Growth Factor Receptor 4. Gastroenterology Research and Practice, 2020 (PubMed: 32587612) [IF=2.0]

Application: WB    Species: Human    Sample: LX-2 cells

Figure 1 FGFR4 is targeted by miR-7-5p in LX-2 cells. (a) The miR-7-5p potential binding sites on FGFR4. (b) mRNA expression of miR-7-5p and FGFR4 in LX-2 cells transfected with the NC and miR-7-5p mimic or inhibitor. (c) Protein expression of FGFR4 in LX-2 cells transfected with the NC and miR-7-5p mimic or inhibitor. (d) The relative luciferase activity in LX-2 cells detected by the dual-luciferase reporter assay. ∗∗P < 0.01, ∗∗∗P < 0.001 versus NC.

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