产品: KCNH2 抗体
货号: AF7540
描述: Rabbit polyclonal antibody to KCNH2
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Bovine, Horse, Rabbit, Dog
蛋白号: Q12809
RRID: AB_2843904

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
KCNH2 Antibody detects endogenous levels of total KCNH2.
RRID:
AB_2843904
引用格式: Affinity Biosciences Cat# AF7540, RRID:AB_2843904.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

eag homolog; Eag-related protein 1; ERG; ERG-1; ERG1; Ether a go go related potassium channel protein; Ether-a-go-go-related gene potassium channel 1; Ether-a-go-go-related protein 1; H ERG; H-ERG; HERG 1; HERG; hERG-1; hERG1; KCNH2; KCNH2_HUMAN; Kv11.1; LQT 2; LQT2; Potassium channel HERG; Potassium voltage gated channel subfamily H (eag related) member 2; Potassium voltage-gated channel subfamily H member 2; SQT1; Voltage gated potassium channel, subfamily H, member 2; Voltage-gated potassium channel subunit Kv11.1;

抗原和靶标

免疫原:

A synthesized peptide derived from human KCNH2, corresponding to a region within C-terminal amino acids.

基因/基因ID:

文献引用

1). Mefloquine improves pulmonary fibrosis by inhibiting the KCNH2/Jak2/Stat3 signaling pathway in macrophages. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2024 (PubMed: 38237352) [IF=6.9]

2). Chelerythrine triggers the prolongation of QT interval and induces cardiotoxicity by promoting the degradation of hERG channels. The Journal of biological chemistry, 2025 (PubMed: 39608718) [IF=4.0]

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