产品: 磷酸化 LATS2 (Ser872) 抗体
货号: AF7440
描述: Rabbit polyclonal antibody to Phospho-LATS2 (Ser872)
应用: WB IF/ICC
文献验证:
反应: Human, Mouse
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
蛋白号: Q9NRM7
RRID: AB_2843880

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
Phospho-LATS2 (Ser872) Antibody detects endogenous levels of LATS2 only when phosphorylated at Ser872.
RRID:
AB_2843880
引用格式: Affinity Biosciences Cat# AF7440, RRID:AB_2843880.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ13161; Kinase phosphorylated during mitosis protein; KPM; Large tumor suppressor homolog 2; Large tumor suppressor homolog 2 Drosophila; Large tumor suppressor kinase 2; LATS large tumor suppressor Drosophila homolog 2; LATS large tumor suppressor homolog 2; Lats2; LATS2_HUMAN; Serine/threonine kinase kpm; Serine/threonine protein kinase kpm; Serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; Warts like kinase; Warts-like kinase;

抗原和靶标

免疫原:

A synthesized peptide derived from human LATS2 around the phosphorylation site of Ser872.

基因/基因ID:

研究领域

· Environmental Information Processing > Signal transduction > Hippo signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Hippo signaling pathway - multiple species.   (View pathway)

文献引用

1). Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenance and chemoresistance in ovarian cancer peritoneal metastasis. Genes & Diseases, 2025 [IF=6.9]

Application: IHC    Species: human    Sample: OCPM tissues

Figure 2. Tissue microarray analysis of the expression of key components in Hippo/YAP signaling in pre- and post-NACT OCPM tissues. A tissue microarray was constructed using 53 pairs of pre- and post-NACT OCPM tissues. The levels of indicated proteins were analyzed by immunohistochemistry. Paired student's t-test; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.

2). Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53. International journal of molecular sciences, 2023 (PubMed: 37894939) [IF=5.6]

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