Phospho-NMDAR2A (Tyr943) Antibody - #AF7362

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产品: 磷酸化 NMDAR2A (Tyr943) 抗体
货号: AF7362
描述: Rabbit polyclonal antibody to Phospho-NMDAR2A (Tyr943)
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Sheep
蛋白号: Q12879
RRID: AB_2843802

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Phospho-NMDAR2A (Tyr943) Antibody detects endogenous levels of NMDAR2A only when phosphorylated at Tyr943.
RRID:
AB_2843802
引用格式: Affinity Biosciences Cat# AF7362, RRID:AB_2843802.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

EPND; FESD; GluN2A; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate receptor; Glutamate receptor ionotropic N methyl D aspartate 2A; GRIN 2A; GRIN2A; hNR2A; LKS; N methyl D aspartate receptor channel, subunit epsilon 1; N Methyl D Aspartate Receptor Subtype 2A; N methyl D aspartate receptor subunit 2A; N-methyl D-aspartate receptor subtype 2A; NMDA receptor subtype 2A; NMDAR 2A; NMDAR2A; NMDE1_HUMAN; NR2A; OTTHUMP00000160135; OTTHUMP00000174531;

抗原和靶标

免疫原:

A synthesized peptide derived from human NMDAR2A around the phosphorylation site of Tyr943.

基因/基因ID:
GRIN2A(2903)

研究领域

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.

· Human Diseases > Neurodegenerative diseases > Amyotrophic lateral sclerosis (ALS).

· Human Diseases > Substance dependence > Cocaine addiction.

· Human Diseases > Substance dependence > Amphetamine addiction.

· Human Diseases > Substance dependence > Alcoholism.

· Human Diseases > Immune diseases > Systemic lupus erythematosus.

· Organismal Systems > Environmental adaptation > Circadian entrainment.

· Organismal Systems > Nervous system > Long-term potentiation.

· Organismal Systems > Nervous system > Glutamatergic synapse.

· Organismal Systems > Nervous system > Dopaminergic synapse.

文献引用

1). Oncostatin M Induces IFITM1 Expression to Inhibit Hepatitis B Virus Replication Via JAK-STAT Signaling. Cellular and molecular gastroenterology and hepatology, 2024 (PubMed: 37879404) [IF=7.1]

Application: WB    Species: human    Sample: HepG2.2.15 cells

Figure 7. OSM induces numerus genes with essential functions in innate immunity. (A) The mRNA levels of antiviral effectors in HepG2.2.15 cells at the indicated time points after OSM treatment (20 ng/mL) were measured by quantitative polymerase chain reaction. The protein levels of S100A9, STING, and LCN2 in HepG2.2.15 cells at 48 hours after OSM treatment (20 ng/mL) were measured by immunoblotting. Unpaired t test. (B, C) The expression of antiviral effectors was analyzed by quantitative polymerase chain reaction and immunoblotting in the indicated groups. One-way analysis of variance. ∗P < .05, ∗∗P < .01, and ∗∗∗P < .001.
2). Remyelination-oriented clemastine treatment attenuates neuropathies of optic nerve and retina in glaucoma. Glia, 2024 (PubMed: 38829008) [IF=5.4]
3). PAG neuronal NMDARs activation mediated morphine-induced hyperalgesia by HMGB1-TLR4 dependent microglial inflammation. Journal of psychiatric research, 2023 (PubMed: 37352811) [IF=3.7]

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