PCNA Antibody - #BF0704

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产品: PCNA 抗体
货号: BF0704
描述: Mouse monoclonal antibody to PCNA
应用: WB IHC ELISA
文献验证: WB
反应: Human, Mouse, Rat
蛋白号: P12004
RRID: AB_2843434

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   规格 价格 库存
 50ul RMB¥ 900 现货
 100ul RMB¥ 1500 现货
 200ul RMB¥ 2000 现货

货期: 当天发货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
WB 1:500-2000, IHC 1:200-1000, FCM 1:200-400, ELISA 1:10000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Monoclonal [AFB14950]
特异性:
PCNA antibody detects endogenous levels of total PCNA.
RRID:
AB_2843434
引用格式: Affinity Biosciences Cat# BF0704, RRID:AB_2843434.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNA_HUMAN; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03;

抗原和靶标

免疫原:

Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli.

基因/基因ID:
PCNA(5111)
描述:
PCNA This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Belongs to the PCNA family. Homotrimer. Forms a complex with activator 1 heteropentamer in the presence of ATP.

研究领域

· Cellular Processes > Cell growth and death > Cell cycle.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Genetic Information Processing > Replication and repair > DNA replication.

· Genetic Information Processing > Replication and repair > Base excision repair.

· Genetic Information Processing > Replication and repair > Nucleotide excision repair.

· Genetic Information Processing > Replication and repair > Mismatch repair.

· Human Diseases > Infectious diseases: Viral > Hepatitis B.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

文献引用

1). Combination of resolvin E1 and lipoxin A4 promotes the resolution of pulpitis by inhibiting NF-κB activation through upregulating sirtuin 7 in dental pulp fibroblasts. CELL PROLIFERATION, 2022 (PubMed: 35411569) [IF=5.9]

Application: WB    Species: rat    Sample: Dental pulp fibroblasts

FIGURE 2 |Effects of the RvE1 and LXA4 combination on NF-κB modification(E) Expression of p65 protein in both cytoplasm and nucleus detected by western blotting, normalized to β-actin (in cytoplasm) or PCNA (in nucleus).
2). Sodium tanshinone IIA sulfonate alleviates fetal growth restriction by mediating aquaporin-3 expression in placental trophoblast cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025 (PubMed: 39825721) [IF=4.4]
3). Role of Annexin A2 isoform 2 on the aggregative growth of dermal papillae cells. BIOSCIENCE REPORTS, 2018 (PubMed: 30341243) [IF=3.8]

Application: WB    Species: human    Sample: passage 3 DPC

Figure 4.| Effect of RNA interference mediated inhibition of Annexin A2 isoform2 expression on biological function of passage 3 DPC.(d)Western blot results showed the expression level of PCNA was suppressed in passage 3 DPC.
4). Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis. International journal of medical sciences, 2023 (PubMed: 37928874) [IF=3.2]
5). Curcumin Protects Human Dermal Fibroblasts Exposed to Hydrogen Peroxide by Regulating Autophagy Level and Reactive Oxygen Species Generation. Journal of burn care & research : official publication of the American Burn Association, 2023 (PubMed: 36857137) [IF=1.5]

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