产品: A-Myb 抗体
货号: AF9007
描述: Rabbit polyclonal antibody to A-Myb
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: P10243
RRID: AB_2843198

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
A-Myb Antibody detects endogenous levels of total A-Myb.
RRID:
AB_2843198
引用格式: Affinity Biosciences Cat# AF9007, RRID:AB_2843198.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

A-Myb; AMYB; MGC120059; MGC120061; Myb related protein A; Myb-like protein 1; Myb-related protein A; MYBA_HUMAN; MYBL1;

抗原和靶标

免疫原:

A synthesized peptide derived from human A-Myb, corresponding to a region within the internal amino acids.

基因/基因ID:

文献引用

1). MYBL1 induces transcriptional activation of ANGPT2 to promote tumor angiogenesis and confer sorafenib resistance in human hepatocellular carcinoma. Cell death & disease, 2022 (PubMed: 35987690) [IF=8.1]

Application: IHC    Species: human    Sample:

Fig. 1: Upregulation of MYBL1 correlates with high EV density and associates with HCC patient prognosis. A IHC staining indicating the MYBL1 and CD31 protein expression in para-tumor tissues and HCC tissues. B MYBL1 were positively correlated with CD31 protein levels in clinical specimens. C Patients with high MYBL1 expression (left), CD31 density (middle), and both MYBL1 and CD31 expression (right) show progression-free survival in HCC patients. D The correlation analysis between the mRNA levels of MYBL1 and angiogenesis in TCGA datasets.

2). Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy. Cell biology and toxicology, 2024 (PubMed: 38797732) [IF=5.3]

Application: WB    Species: human    Sample:

Fig. 2 Different expression of MYBL1, ARHGAP30 and FAM20A was observed in GSE28829, GSE43292 and GSE41571 datasets (A) The intersection of differentially expressed genes of GSE28829, GSE43292 and GSE41571 datasets was selected. (B) Heat map of MYBL1, ARHGAP30 and FAM20A genes in early and late atherosclerotic tissues. (C-E) GEPIA analysis of the three genes MYBL1, ARHGAP30, and FAM20A was performed to obtain box plots of their expression. (F) Immumohistochemical staining was used to determine the protein expression of MYBL1 in advanced atherosclerotic plaques (AA) and normal atherosclerotic plaques (NA) (n = 8). Scale bars = 200 μm or 20 μm. (G)The protein expression of MYBL1 was detected by western blot in early atherosclerosis and advanced atherosclerosis (n = 8). (H) The quantitative analysis of MYBL1 protein expression in early atherosclerosis and advanced atherosclerosis were shown. *p 

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