MPHOSPH10 Antibody - #DF9977

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产品: MPHOSPH10 抗体
货号: DF9977
描述: Rabbit polyclonal antibody to MPHOSPH10
应用: WB
反应: Human
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 20,70 kDa; 79kD(Calculated).
蛋白号: O00566
RRID: AB_2843169

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(100%), Zebrafish(80%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%)
克隆:
Polyclonal
特异性:
MPHOSPH10 Antibody detects endogenous levels of total MPHOSPH10.
RRID:
AB_2843169
引用格式: Affinity Biosciences Cat# DF9977, RRID:AB_2843169.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

M phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); M phase phosphoprotein 10; MPHOSPH 10; Mphosph10; MPP 10; MPP 10P; MPP10; MPP10_HUMAN; MPP10P; U3 small nucleolar ribonucleoprotein protein mpp10;

抗原和靶标

免疫原:
Uniprot:

O00566(MPP10_HUMAN) >>Visit HPA database.

基因/基因ID:
MPHOSPH10(10199)
序列:
MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDIKTAAEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQAGKYSKTVASEKLKQLTKTGKASFIKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKRQDISVHKLKL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Zebrafish
80
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O00566 作为底物

Site PTM Type Enzyme
T10 Phosphorylation
T22 Phosphorylation
S37 Phosphorylation
K38 Ubiquitination
K51 Ubiquitination
S61 Phosphorylation
S120 Phosphorylation
S139 Phosphorylation
S158 Phosphorylation
S163 Phosphorylation
S167 Phosphorylation
S171 Phosphorylation
S178 Phosphorylation
K185 Sumoylation
K189 Acetylation
K193 Acetylation
K197 Acetylation
S198 Phosphorylation
K203 Ubiquitination
S208 Phosphorylation
S242 Phosphorylation
S275 Phosphorylation
T280 Phosphorylation
S289 Phosphorylation
S305 Phosphorylation
S307 Phosphorylation
T309 Phosphorylation
T332 Phosphorylation Q96GD4 (AURKB)
T341 Phosphorylation
S373 Phosphorylation
K376 Ubiquitination
K382 Sumoylation
S399 Phosphorylation
T418 Phosphorylation
Y452 Phosphorylation
Y454 Phosphorylation
T459 Phosphorylation
K466 Ubiquitination
Y477 Phosphorylation
K479 Ubiquitination
K484 Ubiquitination
K498 Ubiquitination
S502 Phosphorylation
K518 Ubiquitination
K559 Acetylation
K564 Acetylation
K574 Acetylation
K609 Acetylation
S629 Phosphorylation
K632 Sumoylation
K641 Methylation

研究背景

功能:

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.

翻译修饰:

Phosphorylated in M (mitotic) phase.

细胞定位:

Nucleus>Nucleolus. Chromosome.
Note: Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with IMP3 and IMP4.

蛋白家族:

Belongs to the MPP10 family.

研究领域

· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.

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